Lmo1 - LIM domain only 1 Gene

Also Known as Ttg1; Rbtn1; Rbtn-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 109594

Summary

Predicted to enable metal ion binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and regulation of T cell homeostatic proliferation. Located in nucleus. Is expressed in several structures, including genitourinary system; hemolymphoid system; nervous system; respiratory system; and sensory organ. Orthologous to human LMO1 (LIM domain only 1). [provided by Alliance of Genome Resources, Apr 2022]

Lmo1 Products (4)

mRNA Protein Name
NM_001302205.2 NP_001289134.1 rhombotin-1 isoform 2
NM_001302206.2 NP_001289135.1 rhombotin-1 isoform 3
NM_001382564.1 NP_001369493.1 rhombotin-1 isoform 1
NM_057173.4 NP_476514.1 rhombotin-1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19323994 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
10373552 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
9819382 MGI
acts upstream of or within regulation of T cell homeostatic proliferation IDA
IDA: Inferred from direct assay
1508213 MGI
Cellular Component GO Annotation Evidence References Source
NOT located in nucleolus IDA
IDA: Inferred from direct assay
1703797 MGI
located in nucleus IDA
IDA: Inferred from direct assay
1703797 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rhombotin-1

  • LIM domain only protein 1

  • LIM only 1

  • T-cell translocation protein 1

  • cysteine-rich protein TTG-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07717 LMO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22223 Lmo1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28745 Lmo1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lmo1 NCBI NCBI:4004