Pygl - liver glycogen phosphorylase Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 110095

Summary

Enables glycogen Phosphorylase activity. Acts upstream of or within glycogen metabolic process; necroptotic process; and response to bacterium. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; cranium; sensory organ; and urinary system. Used to study glycogen storage disease VI. Human ortholog(s) of this gene implicated in glycogen storage disease; glycogen storage disease VI; and lactic acidosis. Orthologous to human PYGL (glycogen Phosphorylase L). [provided by Alliance of Genome Resources, Apr 2022]

Pygl Products (1)

mRNA Protein Name
NM_133198.2 NP_573461.2 glycogen phosphorylase, liver form

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables glycogen phosphorylase activity IDA
IDA: Inferred from direct assay
34673295 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19498109 MGI
Biological Process GO Annotation Evidence References Source
involved in glycogen catabolic process IMP
IMP: Inferred from mutant phenotype
31701076 MGI
acts upstream of or within necroptotic process IGI
IGI: Inferred from genetic interaction
19498109 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycogen phosphorylase, liver form

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11489 PYGL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20806 Pygl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27320 Pygl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pygl NCBI NCBI:5836