ZPBP - zona pellucida binding protein Gene

Also Known as ZPBP1; SPGF66

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 11055

About ZPBP

Cytogenetic location: 7p12.2 Genomic coordinates (GRCh38): 7:49,840,654-50,093,246 (from NCBI)

This gene has 6 transcripts (splice variants), 122 orthologues, 1 paralogue and is associated with 1 phenotype. Restricted expression toward testis (RPKM 37.4).

Summary

ZPBP is one of several proteins that are thought to participate in secondary binding between acrosome-reacted sperm and the egg-specific extracellular matrix, the zona pellucida (McLeskey et al., 1998 [PubMed 9378618]).[supplied by OMIM, Aug 2008]

ZPBP Products (2)

mRNA Protein Name
NM_001159878.2 NP_001153350.1 zona pellucida-binding protein 1 isoform 2 precursor
NM_007009.3 NP_008940.2 zona pellucida-binding protein 1 isoform 1 precursor

ZPBP Protein Structure

Sp38

Sp38: Zona-pellucida-binding protein (Sp38) (86 - 351)

  • 0
  • 100
  • 200
  • 300
  • 351 a.a.
Protein Preferred Names Protein Names

zona pellucida-binding protein 1

  • inner acrosomal membrane IAM38

Related Diseases

Diseases Alias
Spermatogenic Failure 66

  • SPGF66
Spermatogenic Failure 9

  • Male Infertility Due To Globozoospermia

  • SPGF9

  • Male Infertility Due To Round-Headed Spermatozoa

  • Globozoospermia, Complete

  • Globozoospermia, Total

  • Globozoospermia

  • Globozoospermia Syndrome

  • Round-Headed Sperm Syndrome

  • Globozoospermia Complete

  • Globozoospermia Total
Spermatogenic Failure

  • Azoospermia

  • Spgf

  • Spermatogenic Failure, Susceptibility To

  • Absent Sperm

  • Aspermatogenesis

  • Infertility Due To Azoospermia

  • Hypospermatogenesis

  • Azoospermatism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS29490 Zpbp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16190 ZPBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ZPBP VGNC VGNC:108457
Bos taurus ZPBP VGNC VGNC:37368
Mus musculus ZPBP MGD MGI:1855701
Felis catus ZPBP VGNC VGNC:67375
Canis familiaris ZPBP VGNC VGNC:48844
Rattus norvegicus ZPBP RGD RGD:1563985
Others ZPBP NCBI