Pitx1 - paired-like homeodomain 1 Gene

Also Known as Bft

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 113983

Summary

Enables DNA-binding transcription factor activity. Involved in regulation of transcription, DNA-templated. Predicted to be located in cytoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in clubfoot. Orthologous to human PITX1 (paired like homeodomain 1). [provided by Alliance of Genome Resources, Apr 2022]

Pitx1 Products (1)

mRNA Protein Name
NM_053624.2 NP_446076.1 pituitary homeobox 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
12223489 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
12223489 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pituitary homeobox 1

  • homeobox protein PITX1

  • paired-like homeodomain transcription factor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10581 PITX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21023 Pitx1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27540 Pitx1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pitx1 NCBI NCBI:5307