Cited2 - Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 Gene

Also Known as Mrg1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114490

Summary

Predicted to enable several functions, including LBD domain binding activity; Histone Acetyltransferase binding activity; and transcription coactivator activity. Involved in several processes, including cell aging; negative regulation of cardiac muscle cell proliferation; and regulation of gene expression. Predicted to be located in chromatin and cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Used to study osteosarcoma. Biomarker of brain ischemia. Human ortholog(s) of this gene implicated in atrial heart septal defect 8 and ventricular septal defect. Orthologous to human CITED2 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2). [provided by Alliance of Genome Resources, Apr 2022]

Cited2 Products (1)

mRNA Protein Name
NM_053698.3 NP_446150.1 cbp/p300-interacting transactivator 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to growth factor stimulus IEP
IEP: Inferred from expression pattern
19013137 RGD
involved in cellular senescence IEP
IEP: Inferred from expression pattern
20569237 RGD
involved in negative regulation of cardiac muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
26240138 RGD
involved in negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
26240138 RGD
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
26240138 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
20826544 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cbp/p300-interacting transactivator 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02729 CITED2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21106 Cited2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27625 Cited2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cited2 NCBI NCBI:10370