Pi4k2a - phosphatidylinositol 4-kinase type 2 alpha Gene

Also Known as Pi4KII

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114554

Summary

Enables 1-phosphatidylinositol 4-kinase activity. Involved in basophil degranulation. Located in several cellular components, including cytoplasmic vesicle membrane; growing cell tip; and perikaryon. Part of protein-containing complex. Orthologous to human PI4K2A (phosphatidylinositol 4-kinase type 2 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Pi4k2a Products (1)

mRNA Protein Name
NM_053735.2 NP_446187.1 phosphatidylinositol 4-kinase type 2-alpha

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 1-phosphatidylinositol 4-kinase activity IDA
IDA: Inferred from direct assay
12646710 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
18256276 RGD
Biological Process GO Annotation Evidence References Source
involved in basophil degranulation IMP
IMP: Inferred from mutant phenotype
17122963 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
21998198 RGD
located in early endosome membrane IDA
IDA: Inferred from direct assay
18256276 RGD
located in endosome IDA
IDA: Inferred from direct assay
21998198 RGD
located in exocytic vesicle IDA
IDA: Inferred from direct assay
17122963 RGD
located in growing cell tip IDA
IDA: Inferred from direct assay
21998198 RGD
located in neuron projection IDA
IDA: Inferred from direct assay
21998198 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
21998198 RGD
located in perikaryon IDA
IDA: Inferred from direct assay
12646710 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
18256276 RGD
located in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
12646710 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylinositol 4-kinase type 2-alpha

  • 55 kDa type II phosphatidylinositol 4-kinase

  • phosphatidylinositol 4-kinase type II

  • phosphatidylinositol 4-kinase type II-alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-115675 NC03 Inhibitor 98.79% Unkown
HY-RS10464 PI4K2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20578 Pi4k2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27086 Pi4k2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pi4k2a NCBI NCBI:55361