Abcg5 - ATP binding cassette subfamily G member 5 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114628

Summary

Predicted to enable ATPase-coupled transmembrane transporter activity and protein heterodimerization activity. Predicted to contribute to ATP binding activity; ATP hydrolysis activity; and Cholesterol transfer activity. Involved in several processes, including bile acid signaling pathway; lipid homeostasis; and response to muscle activity. Predicted to be located in apical plasma membrane. Predicted to be integral component of plasma membrane. Predicted to be part of ATP-binding activity cassette (ABC) transporter complex and receptor complex. Used to study sitosterolemia. Biomarker of cholestasis; non-alcoholic fatty liver disease; and obesity. Human ortholog(s) of this gene implicated in arteriosclerosis and sitosterolemia. Orthologous to human ABCG5 (ATP binding cassette subfamily G member 5). [provided by Alliance of Genome Resources, Apr 2022]

Abcg5 Products (1)

mRNA Protein Name
NM_053754.2 NP_446206.2 ATP-binding cassette sub-family G member 5

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cholesterol homeostasis IEP
IEP: Inferred from expression pattern
23117815 RGD
involved in response to ionizing radiation IEP
IEP: Inferred from expression pattern
17132608 RGD
involved in response to muscle activity IEP
IEP: Inferred from expression pattern
23117815 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
15710224 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
23117815 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
17109865 RGD
involved in triglyceride homeostasis IEP
IEP: Inferred from expression pattern
23117815 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-binding cassette sub-family G member 5

  • ATP-binding cassette sub-family G (WHITE) member 5 (sterolin 1)

  • ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1)

  • ATP-binding cassette, subfamily G (WHITE), member 5

  • sterolin 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0288 Lycorine 99.98% Unkown
HY-N9516A Taurodehydrocholic acid sodium 99.87% Unkown
HY-N0288R Lycorine (Standard) 99.54% Unkown
HY-N9516 Taurodehydrocholic acid / Unkown
HY-RS00081 ABCG5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181520 ABCA1 inducer 3 Inducer / Unkown
HY-N9516AR Taurodehydrocholic acid sodium (Standard) / Unkown
HY-RS17755 Abcg5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24222 Abcg5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abcg5 NCBI NCBI:64240