Ahrr - aryl-hydrocarbon receptor repressor Gene

Also Known as mKIAA1234

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11624

Summary

This gene encodes a protein that represses aryl hydrocarbon receptor-dependent signaling. The encoded protein competes with the Aryl Hydrocarbon Receptor transcription factor for heterodimerization with the Aryl Hydrocarbon Receptor nuclear translocator protein and binding to xenobiotic response element (XRE) sequence in many genes. This protein is implicated in the regulation of cell growth and differentiation as well as mediating dioxin toxicity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]

Ahrr Products (2)

mRNA Protein Name
NM_001317351.1 NP_001304280.1 aryl hydrocarbon receptor repressor isoform 2
NM_009644.3 NP_033774.1 aryl hydrocarbon receptor repressor isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
19251700 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
19251700 MGI
involved in positive regulation of protein sumoylation IDA
IDA: Inferred from direct assay
19251700 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
19251700 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

aryl hydrocarbon receptor repressor

  • ahR repressor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00484 AHRR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03441 CYP1A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16737 Cyp1a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19573 Ahrr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23174 Cyp1a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26070 Ahrr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W517092 1,2,3,4,7,8,9-Heptachlorodibenzofuran / Unkown
HY-W775354 1,2,3,4,7,8-Hexachlorodibenzofuran / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ahrr NCBI NCBI:57491