Fgfrl1 - fibroblast growth factor receptor-like 1 Gene

Also Known as FGFR5; FGFR5beta; FGFR5gamma

Species: Mus musculus

Gene Type: protein coding
Gene ID: 116701

Summary

Enables Fibroblast Growth Factor binding activity and fibroblast growth factor-activated receptor activity. Acts upstream of or within animal organ development; negative regulation of cell population proliferation; and skeletal system development. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; musculoskeletal system; respiratory system; and sensory organ. Used to study Wolf-Hirschhorn syndrome. Orthologous to human FGFRL1 (Fibroblast Growth Factor receptor like 1). [provided by Alliance of Genome Resources, Apr 2022]

Fgfrl1 Products (2)

mRNA Protein Name
NM_001164259.1 NP_001157731.1 fibroblast growth factor receptor-like 1 isoform 2 precursor
NM_054071.2 NP_473412.1 fibroblast growth factor receptor-like 1 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables fibroblast growth factor binding IPI
IPI: Inferred from physical interaction
11418238 MGI
enables fibroblast growth factor receptor activity IDA
IDA: Inferred from direct assay
12813049 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within diaphragm development IMP
IMP: Inferred from mutant phenotype
17986259 MGI
acts upstream of or within heart valve morphogenesis IMP
IMP: Inferred from mutant phenotype
19383940 MGI
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
12813049 MGI
acts upstream of or within skeletal system development IMP
IMP: Inferred from mutant phenotype
19383940 MGI
acts upstream of or within ventricular septum morphogenesis IMP
IMP: Inferred from mutant phenotype
19383940 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
12813049 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor receptor-like 1

  • FGF receptor-like protein 1

  • fibroblast growth factor receptor 5

Recombinant Fgfrl1 Proteins

Cat. No. Product Name Accession Purity
HY-P76343 FGFRL1 Protein, Mouse (HEK293, His) Q91V87 (A21-P374) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04924 FGFRL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174686 Human FGFRL1 mRNA / Unkown
HY-RS20157 Fgfrl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26661 Fgfrl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgfrl1 NCBI NCBI:53834