Ppat - phosphoribosyl pyrophosphate amidotransferase Gene

Also Known as Atase

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117544

Summary

Enables amidophosphoribosyltransferase activity and identical protein binding activity. Involved in several processes, including animal organ development; cellular response to Insulin stimulus; and glutamine catabolic process. Biomarker of hepatocellular carcinoma and renal cell carcinoma. Orthologous to human PPAT (phosphoribosyl pyrophosphate amidotransferase). [provided by Alliance of Genome Resources, Apr 2022]

Ppat Products (1)

mRNA Protein Name
NM_057198.2 NP_476546.1 amidophosphoribosyltransferase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables amidophosphoribosyltransferase activity IDA
IDA: Inferred from direct assay
8463258 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
8463258 RGD
Biological Process GO Annotation Evidence References Source
involved in G1/S transition of mitotic cell cycle IEP
IEP: Inferred from expression pattern
7742366 RGD
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
2430469 RGD
involved in cellular response to insulin stimulus IEP
IEP: Inferred from expression pattern
2185659 RGD
involved in cellular response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
3012070 RGD
involved in glutamine catabolic process IDA
IDA: Inferred from direct assay
8463258 RGD
involved in kidney development IEP
IEP: Inferred from expression pattern
476627 RGD
involved in lactation IEP
IEP: Inferred from expression pattern
2451510 RGD
involved in maternal process involved in female pregnancy IEP
IEP: Inferred from expression pattern
2451510 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
7078346 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

amidophosphoribosyltransferase

  • GPAT

  • glutamine phosphoribosylpyrophosphate amidotransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02946 COASY Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10932 PPAT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18044 Ppat Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18993 Coasy Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24518 Ppat Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppat NCBI NCBI:5471