Bard1 - BRCA1 associated RING domain 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12021

Summary

Predicted to enable RNA binding activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of protein export from nucleus; protein K6-linked ubiquitination; and regulation of apoptotic process. Predicted to act upstream of or within DNA repair. Located in nucleus. Is expressed in genitourinary system; limb; and spleen. Used to study breast Cancer. Human ortholog(s) of this gene implicated in breast Cancer and ovarian Cancer. Orthologous to human BARD1 (BRCA1 associated RING domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Bard1 Products (1)

mRNA Protein Name
NM_007525.3 NP_031551.1 BRCA1-associated RING domain protein 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
11555636 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BRCA1-associated RING domain protein 1

  • BARD-1

  • RING-type E3 ubiquitin transferase BARD1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01365 BARD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174563 Human OLA1 mRNA / Unkown
HY-RS20367 Bard1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26877 Bard1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bard1 NCBI NCBI:580