Camk2g - calcium/calmodulin-dependent protein kinase II gamma Gene

Also Known as Camkg

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12325

About Camk2g

Chromosome 14: 20,784,943-20,844,156 reverse strand.GRCm39:CM001007.3

This gene has 17 transcripts (splice variants), 297 orthologues, 21 paralogues and is associated with 6 phenotypes. Broad expression in cortex adult (RPKM 49.3), cerebellum adult (RPKM 39.7) and 26 other tissues.

Summary

Enables protein serine/threonine kinase activity. Involved in regulation of neuron projection development and regulation of relaxation of cardiac muscle. Acts upstream of or within G1/S transition of mitotic cell cycle; calcium ion transport; and protein autophosphorylation. Located in postsynaptic density. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human CAMK2G (calcium/Calmodulin dependent protein kinase II gamma). [provided by Alliance of Genome Resources, Apr 2022]

Camk2g Products (4)

mRNA Protein Name
NM_178597.5 NP_848712.2 calcium/calmodulin-dependent protein kinase type II subunit gamma isoform 1
NM_001360186.1 NP_001347115.1 calcium/calmodulin-dependent protein kinase type II subunit gamma isoform 4
NM_001039138.2 NP_001034227.1 calcium/calmodulin-dependent protein kinase type II subunit gamma isoform 2
NM_001039139.2 NP_001034228.1 calcium/calmodulin-dependent protein kinase type II subunit gamma isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium/calmodulin-dependent protein kinase activity IDA
IDA: Inferred from direct assay
11972023 MGI
enables protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
12660151 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within G1/S transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
12660151 MGI
acts upstream of or within calcium ion transport IMP
IMP: Inferred from mutant phenotype
12660151 MGI
acts upstream of or within protein autophosphorylation IMP
IMP: Inferred from mutant phenotype
12660151 MGI
involved in regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
30184290 MGI
involved in regulation of relaxation of cardiac muscle IGI
IGI: Inferred from genetic interaction
23283722 MGI
Cellular Component GO Annotation Evidence References Source
located in postsynaptic density IDA
IDA: Inferred from direct assay
17114649 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Camk2g Protein Structure

STKc_CaMKII

STKc_CaMKII: cd14086 (11 - 302)

CaMKII_AD

CaMKII_AD: pfam08332 (394 - 521)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 527 a.a.
Protein Preferred Names Protein Names

calcium/calmodulin-dependent protein kinase type II subunit gamma

  • Ca2+/calmodulin-dependent protein kinase II

  • CaMK II

  • caMK-II subunit gamma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01859 CAMK2G Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01860 Camk2g Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01861 CAMK2G Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Camk2g NCBI NCBI:818