LTB4R - leukotriene B4 receptor Gene

Also Known as BLT1; BLTR; P2Y7; GPR16; LTBR1; P2RY7; CMKRL1; LTB4R1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1241

About LTB4R

Cytogenetic location: 14q12 Genomic coordinates (GRCh38): 14:24,311,502-24,318,036 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 141 orthologues and 17 paralogues. Biased expression in skin (RPKM 33.9), esophagus (RPKM 9.6) and 10 other tissues.

Summary

Predicted to enable G protein-coupled peptide receptor activity and leukotriene B4 receptor activity. Predicted to be involved in inflammatory response and neuropeptide signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

LTB4R Products (2)

mRNA Protein Name
NM_001143919.3 NP_001137391.1 leukotriene B4 receptor 1
NM_181657.3 NP_858043.1 leukotriene B4 receptor 1

LTB4R Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (35 - 285)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
Protein Preferred Names Protein Names

leukotriene B4 receptor 1

  • G protein-coupled receptor 16

  • LTB4-R 1

  • LTB4-R1

  • P2Y purinoceptor 7

  • chemoattractant receptor-like 1

  • chemokine receptor-like 1

  • purinergic receptor P2Y, G-protein coupled, 7

Related Diseases

Diseases Alias
Entropion
Trichomoniasis

  • Trichomonas Infection

  • Trichomonas Infections

  • Disease Due To Trichomonadidae

  • Infection By Trichomonas

  • Trichomonadosis

  • Trichomonas Pruritus

  • Trichomonosis

  • Tricomoniasis
Psoriasis 5

  • PSORS5

  • Psoriasis Susceptibility 5

  • Psoriasis 5, Susceptibility To
Persistent Mild Asthma
Inflammatory Bowel Disease

  • Inflammatory Bowel Diseases

  • Bowel Disease, Inflammatory
Asthma

  • Chronic Obstructive Asthma

  • Asthma, Diminished Response To Antileukotriene Treatment In

  • Bronchial Hyperreactivity

  • Asthma, Susceptibility To

  • Asthma, Bronchial

  • Asthma, Protection Against

  • Asthma, Nocturnal, Susceptibility To

  • Nocturnal Asthma

  • Asthma-Related Traits

  • Asthma-Related Traits, Susceptibility To

  • Asthma, Nocturnal

  • Chronic Obstructive Asthma With Acute Exacerbation

  • Chronic Obstructive Asthma With Status Asthmaticus

  • Exercise Induced Asthma

  • Exercise-Induced Asthma

  • Bronchial Asthma

  • Asthma, Exercise-Induced

  • Idiosyncratic Asthma

  • Unspecified Asthma With Acute Exacerbation

  • Asthma, Unspecified, With Stated Status Asthmaticus

  • Status Asthmaticus Nos

  • Acute Severe Asthma

  • Acute Severe Bronchial Asthma

  • Status Asthma

  • Status Post Asthmaticus
Dirofilariasis

  • Dirofilaria Infectious Disease

  • Infection By Dirofilaria
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07873 LTB4R Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07874 Ltb4r Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07875 Ltb4r1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07876 LTB4R2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus LTB4R RGD RGD:620410
Macaca mulatta LTB4R VGNC VGNC:74455
Felis catus LTB4R VGNC VGNC:68102
Mus musculus LTB4R MGD MGI:1309472
Bos taurus LTB4R VGNC VGNC:31069
Canis familiaris LTB4R VGNC VGNC:42855
Others LTB4R NCBI