Ch25h - cholesterol 25-hydroxylase Gene

Also Known as m25OH

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12642

Summary

Enables Cholesterol 25-hydroxylase activity. Involved in B cell chemotaxis. Acts upstream of or within Cholesterol metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; respiratory system; and skin. Orthologous to human CH25H (Cholesterol 25-hydroxylase). [provided by Alliance of Genome Resources, Apr 2022]

Ch25h Products (1)

mRNA Protein Name
NM_009890.2 NP_034020.1 cholesterol 25-hydroxylase
Molecular Function GO Annotation Evidence References Source
enables cholesterol 25-hydroxylase activity IDA
IDA: Inferred from direct assay
29033131 MGI
enables cholesterol 25-hydroxylase activity IMP
IMP: Inferred from mutant phenotype
22999953 MGI
enables steroid hydroxylase activity IDA
IDA: Inferred from direct assay
9852097 MGI
Biological Process GO Annotation Evidence References Source
involved in B cell chemotaxis IMP
IMP: Inferred from mutant phenotype
22999953 MGI
acts upstream of or within cholesterol metabolic process IDA
IDA: Inferred from direct assay
9852097 MGI
involved in negative regulation of cholesterol metabolic process IDA
IDA: Inferred from direct assay
29033131 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cholesterol 25-hydroxylase

  • cholesterol 25-monooxygenase

Orthologs Information

Species Symbol Source ID
Homo sapiens Ch25h NCBI NCBI:9023