ADAD1 - adenosine deaminase domain containing 1 Gene

Homo sapiens

Also known as Tenr

Gene ID: 132612 | Gene type: protein coding

About ADAD1

Cytogenetic location: 4q27 Genomic coordinates (GRCh38): 4:122,379,011-122,429,784 (from NCBI)

This gene has 7 transcripts (splice variants), 216 orthologues and 14 paralogues. Restricted expression toward testis (RPKM 52.2).

Summary

Predicted to enable double-stranded RNA Adenosine Deaminase activity; double-stranded RNA binding activity; and tRNA-specific Adenosine Deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to act upstream of or within spermatid development. Predicted to be located in nucleus. Predicted to be active in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

ADAD1 Products(3)

mRNA	Protein	Name
NM_001159285.2	NP_001152757.1	adenosine deaminase domain-containing protein 1 isoform 2
NM_001159295.2	NP_001152767.1	adenosine deaminase domain-containing protein 1 isoform 3
NM_139243.4	NP_640336.1	adenosine deaminase domain-containing protein 1 isoform 1

ADAD1 Protein Structure

dsrm

A_deamin

0
100
200
300
400
500
576 a.a.

Protein Preferred Names

Protein Names

adenosine deaminase domain-containing protein 1

adenosine deaminase domain containing 1 (testis-specific)

Related Diseases

Diseases

Alias

Myxoid Liposarcoma

Myxoid/Round Cell Liposarcoma	Liposarcoma, Myxoid
Mrcls	Myxoliposarcoma
MXLIPO	Liposarcoma Myxoid
Liposarcoma

Celiac Disease 1

Celiac Disease	Coeliac Disease
Celiac Sprue	Celiac Disease, Susceptibility To
Gluten-Sensitive Enteropathy	Nontropical Sprue
Sprue	CELIAC1
Celiac Disease, Susceptibility To, 1	Celiac Sprue 1
Celiac Sprue, Susceptibility To, 1	Gluten-Sensitive Enteropathy 1
Gluten-Sensitive Enteropathy, Susceptibility To, 1	Idiopathic Steatorrhea
Cœliac Disease	Gluten Intolerance
Gluten-Induced Enteropathy	Gluten Enteropathy
Celiac Disease, Susceptibility To, Type 1	Childhood Celiac Disease
Coeliac Rickets	Gee Disease
Gee-Herter Disease	Heubner-Herter Disease
Idiopathic Steatorrhoea	Thaysen'S Disease
Herter Gee Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00262	ADAD1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ADAD1	VGNC	VGNC:25601
Macaca mulatta	ADAD1	VGNC	VGNC:69553
Rattus norvegicus	ADAD1	RGD	RGD:1359309
Felis catus	ADAD1	VGNC	VGNC:59570
Canis familiaris	ADAD1	VGNC	VGNC:37570
Mus musculus	ADAD1	MGD	MGI:103258

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