ADAD1 - adenosine deaminase domain containing 1 Gene

Also Known as Tenr

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 132612

About ADAD1

Cytogenetic location: 4q27 Genomic coordinates (GRCh38): 4:122,379,011-122,429,784 (from NCBI)

This gene has 7 transcripts (splice variants), 216 orthologues and 14 paralogues. Restricted expression toward testis (RPKM 52.2).

Summary

Predicted to enable double-stranded RNA Adenosine Deaminase activity; double-stranded RNA binding activity; and tRNA-specific Adenosine Deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to act upstream of or within spermatid development. Predicted to be located in nucleus. Predicted to be active in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

ADAD1 Products (3)

mRNA Protein Name
NM_001159285.2 NP_001152757.1 adenosine deaminase domain-containing protein 1 isoform 2
NM_001159295.2 NP_001152767.1 adenosine deaminase domain-containing protein 1 isoform 3
NM_139243.4 NP_640336.1 adenosine deaminase domain-containing protein 1 isoform 1

ADAD1 Protein Structure

dsrm

dsrm: Double-stranded RNA binding motif (97 - 162)

A_deamin

A_deamin: Adenosine-deaminase (editase) domain (249 - 569)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 576 a.a.
Protein Preferred Names Protein Names

adenosine deaminase domain-containing protein 1

  • adenosine deaminase domain containing 1 (testis-specific)

Related Diseases

Diseases Alias
Myxoid Liposarcoma

  • Myxoid/Round Cell Liposarcoma

  • Liposarcoma, Myxoid

  • Mrcls

  • Myxoliposarcoma

  • MXLIPO

  • Liposarcoma Myxoid

  • Liposarcoma
Celiac Disease 1

  • Celiac Disease

  • Coeliac Disease

  • Celiac Sprue

  • Celiac Disease, Susceptibility To

  • Gluten-Sensitive Enteropathy

  • Nontropical Sprue

  • Sprue

  • CELIAC1

  • Celiac Disease, Susceptibility To, 1

  • Celiac Sprue 1

  • Celiac Sprue, Susceptibility To, 1

  • Gluten-Sensitive Enteropathy 1

  • Gluten-Sensitive Enteropathy, Susceptibility To, 1

  • Idiopathic Steatorrhea

  • Cœliac Disease

  • Gluten Intolerance

  • Gluten-Induced Enteropathy

  • Gluten Enteropathy

  • Celiac Disease, Susceptibility To, Type 1

  • Childhood Celiac Disease

  • Coeliac Rickets

  • Gee Disease

  • Gee-Herter Disease

  • Heubner-Herter Disease

  • Idiopathic Steatorrhoea

  • Thaysen'S Disease

  • Herter Gee Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00262 ADAD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ADAD1 VGNC VGNC:25601
Macaca mulatta ADAD1 VGNC VGNC:69553
Rattus norvegicus ADAD1 RGD RGD:1359309
Felis catus ADAD1 VGNC VGNC:59570
Canis familiaris ADAD1 VGNC VGNC:37570
Mus musculus ADAD1 MGD MGI:103258
Others ADAD1 NCBI