Trdmt1 - tRNA aspartic acid methyltransferase 1 Gene

Also Known as Dnmt2; Rnmt2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13434

Summary

Enables tRNA (cytosine-5-)-methyltransferase activity. Involved in tRNA stabilization. Acts upstream of or within tRNA methylation. Predicted to be located in cytoplasm. Is expressed in several structures, including central nervous system; olfactory epithelium; reproductive system; thymus; and thyroid gland. Orthologous to human TRDMT1 (tRNA aspartic acid methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Trdmt1 Products (1)

mRNA Protein Name
NM_010067.4 NP_034197.3 tRNA (cytosine(38)-C(5))-methyltransferase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables tRNA (cytidine-5-)-methyltransferase activity IMP
IMP: Inferred from mutant phenotype
22885326 MGI
enables tRNA methyltransferase activity IMP
IMP: Inferred from mutant phenotype
16424344 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within tRNA methylation IMP
IMP: Inferred from mutant phenotype
16424344 MGI
involved in tRNA methylation IMP
IMP: Inferred from mutant phenotype
22885326 MGI
involved in tRNA stabilization IMP
IMP: Inferred from mutant phenotype
22885326 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tRNA (cytosine(38)-C(5))-methyltransferase

  • DNA (cytosine-5)-methyltransferase-like protein 2

  • DNA MTase homolog MmuIIP

  • DNA methyltransferase 2

  • DNA methyltransferase homolog MmuIIP

  • m.MmuIIP

  • met-2

  • tRNA (cytosine-5-)-methyltransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14999 TRDMT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19533 Trdmt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26029 Trdmt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trdmt1 NCBI NCBI:1787