PXDNL - peroxidasin like Gene

Also Known as PMR1; PRM1; VPO2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 137902

About PXDNL

Cytogenetic location: 8q11.22-q11.23 Genomic coordinates (GRCh38): 8:51,319,577-51,809,445 (from NCBI)

This gene has 4 transcripts (splice variants), 71 orthologues and 5 paralogues. Biased expression in heart (RPKM 10.6), testis (RPKM 1.5) and 1 other tissue.

Summary

Predicted to enable heme binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

PXDNL Products (1)

mRNA Protein Name
NM_144651.5 NP_653252.4 probable oxidoreductase PXDNL precursor

PXDNL Protein Structure

LRR_8

LRR_8: Leucine rich repeat (53 - 110)

LRR_8

LRR_8: Leucine rich repeat (123 - 182)

I-set

I-set: Immunoglobulin I-set domain (234 - 317)

I-set

I-set: Immunoglobulin I-set domain (330 - 415)

I-set

I-set: Immunoglobulin I-set domain (419 - 505)

I-set

I-set: Immunoglobulin I-set domain (512 - 597)

An_peroxidase

An_peroxidase: Animal haem peroxidase (727 - 1272)

VWC

VWC: von Willebrand factor type C domain (1398 - 1450)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1463 a.a.
Protein Preferred Names Protein Names

probable oxidoreductase PXDNL

peroxidasin-like protein

  • cardiac peroxidase

Related Diseases

Diseases Alias
Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome 3

  • Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome 3

  • EEC3

  • Eec Syndrome 3

  • Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome, Type 3
Crisponi/Cold-Induced Sweating Syndrome 1

  • Crisponi Syndrome

  • Cold-Induced Sweating Syndrome 1

  • CISS1

  • Sohar-Crisponi Syndrome

  • Muscle Contractions, Tetanoform, With Characteristic Face, Camptodactyly, Hyperthermia, And Sudden Death

  • Muscle Contractions Tetanoform With Characteristic Face Camptodactyly Hyperthermia And Sudden Death
Hypertrophy Of Breast

  • Breasts Enlarged

  • Large Breast

  • Hypertrophy Of Breast Nos

  • Hypertrophy Of Male Breast

  • Hypertrophic Breast

  • Excessive Development Of Breast

  • Macromastia

  • Mastoplastia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11480 PXDNL Human Pre-designed siRNA Set A Pre-designed Set / Unkown