Gjc1 - gap junction protein, gamma 1 Gene

Also Known as Cx45; Cxnq; Gja7; Cnx45; Gja-7; C130009G16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14615

Summary

Enables gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling and ion channel activity. Involved in AV node cell to bundle of His cell communication by electrical coupling and gap junction assembly. Acts upstream of or within several processes, including chemical synaptic transmission; circulatory system development; and visual perception. Located in gap junction. Part of connexin complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and integumental system. Orthologous to human GJC1 (Gap Junction Protein gamma 1). [provided by Alliance of Genome Resources, Apr 2022]

Gjc1 Products (4)

mRNA Protein Name
NM_001159382.1 NP_001152854.1 gap junction gamma-1 protein
NM_001159383.1 NP_001152855.1 gap junction gamma-1 protein
NM_001359040.1 NP_001345969.1 gap junction gamma-1 protein
NM_008122.3 NP_032148.1 gap junction gamma-1 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling IMP
IMP: Inferred from mutant phenotype
22982984 MGI
enables monoatomic ion channel activity IGI
IGI: Inferred from genetic interaction
15879306 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18055446 MGI
Biological Process GO Annotation Evidence References Source
involved in AV node cell to bundle of His cell communication by electrical coupling IMP
IMP: Inferred from mutant phenotype
22982984 MGI
acts upstream of or within cardiac muscle tissue development IMP
IMP: Inferred from mutant phenotype
14681043 MGI
acts upstream of or within cell development IMP
IMP: Inferred from mutant phenotype
14681043 MGI
acts upstream of or within cell-cell signaling IMP
IMP: Inferred from mutant phenotype
15659592 MGI
acts upstream of or within chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
15659592 MGI
involved in gap junction assembly IMP
IMP: Inferred from mutant phenotype
22982984 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
14681043 MGI
acts upstream of or within vasculogenesis IMP
IMP: Inferred from mutant phenotype
10976050 MGI
acts upstream of or within visual perception IMP
IMP: Inferred from mutant phenotype
15659592 MGI
Cellular Component GO Annotation Evidence References Source
part of connexin complex IGI
IGI: Inferred from genetic interaction
15879306 MGI
located in gap junction IDA
IDA: Inferred from direct assay
11922902 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction gamma-1 protein

  • connexin q

  • connexin-45

  • gap junction alpha-7 protein

  • gap junction membrane channel protein alpha 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS05452 GJC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05456 GJD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22185 Gjc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28707 Gjc1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gjc1 NCBI NCBI:10052