Gjb3 - gap junction protein, beta 3 Gene

Also Known as Cx31; Cxnc; Cnx31; Gjb-3; D4Wsu144e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14620

Summary

Predicted to enable gap junction channel activity. Acts upstream of or within placenta development. Located in cytoplasm and gap junction. Is expressed in several structures, including alimentary system; early conceptus; integumental system; reproductive system; and sensory organ. Used to study erythrokeratodermia variabilis. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 2B; autosomal recessive nonsyndromic deafness 1A; erythrokeratodermia variabilis; and erythrokeratodermia variabilis et progressiva 1. Orthologous to human GJB3 (Gap Junction Protein beta 3). [provided by Alliance of Genome Resources, Apr 2022]

Gjb3 Products (2)

mRNA Protein Name
NM_001160012.2 NP_001153484.1 gap junction beta-3 protein
NM_008126.3 NP_032152.1 gap junction beta-3 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18055446 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within placenta development IMP
IMP: Inferred from mutant phenotype
15895417 MGI
Cellular Component GO Annotation Evidence References Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
7889986 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
7889986 MGI
located in gap junction IDA
IDA: Inferred from direct assay
14595769 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction beta-3 protein

  • connexin c

  • connexin-31

  • gap junction membrane channel protein beta 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05448 GJB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22183 Gjb3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28705 Gjb3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gjb3 NCBI NCBI:2707