Gnaz - guanine nucleotide binding protein, alpha z subunit Gene

Also Known as Gz

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14687

Summary

Predicted to enable G protein-coupled serotonin receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Acts upstream of or within G protein-coupled serotonin receptor signaling pathway. Located in cell body and dendrite. Is expressed in brain; early conceptus; early tubule; ganglia; and gonad. Orthologous to human GNAZ (G protein subunit alpha z). [provided by Alliance of Genome Resources, Apr 2022]

Gnaz Products (2)

mRNA Protein Name
NM_001358848.1 NP_001345777.1 guanine nucleotide-binding protein G(z) subunit alpha
NM_010311.4 NP_034441.1 guanine nucleotide-binding protein G(z) subunit alpha

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables adenylate cyclase inhibitor activity IMP
IMP: Inferred from mutant phenotype
18096703 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within G protein-coupled serotonin receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
15931062 MGI
involved in negative regulation of insulin secretion IMP
IMP: Inferred from mutant phenotype
18096703 MGI
Cellular Component GO Annotation Evidence References Source
located in cell body IDA
IDA: Inferred from direct assay
11685543 MGI
located in dendrite IDA
IDA: Inferred from direct assay
11685543 MGI
is active in plasma membrane IDA
IDA: Inferred from direct assay
21220323 MGI
is active in synapse IDA
IDA: Inferred from direct assay
19446022 MGI
is active in synapse IEP
IEP: Inferred from expression pattern
19446022 MGI
is active in synapse IMP
IMP: Inferred from mutant phenotype
19446022 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(z) subunit alpha

  • g(x) alpha chain

  • gz-alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05544 GNAZ Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19138 Gnaz Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25628 Gnaz Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnaz NCBI NCBI:2781