Grik3 - glutamate receptor, ionotropic, kainate 3 Gene
Also Known as GluK3; Glur7; Glur-7; GluR7-3; 9630027E11
Species: Mus musculus
Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Transcript variants encoding different isoforms have been described for this gene, however, their full-length nature is not known. [provided by RefSeq, Jul 2008]
Grik3 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001081097.3 | NP_001074566.1 | glutamate receptor ionotropic, kainate 3 precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables glutamate-gated calcium ion channel activity |
IDA
IDA: Inferred from direct assay
|
20007474 | MGI |
| enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential |
IDA
IDA: Inferred from direct assay
|
17620617 | MGI |
| enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential |
IEP
IEP: Inferred from expression pattern
|
17620617 | MGI |
| enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential |
IMP
IMP: Inferred from mutant phenotype
|
17620617 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
15805114 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| is active in glutamatergic synapse |
IDA
IDA: Inferred from direct assay
|
17620617 | MGI |
| is active in glutamatergic synapse |
IEP
IEP: Inferred from expression pattern
|
17620617 | MGI |
| is active in glutamatergic synapse |
IMP
IMP: Inferred from mutant phenotype
|
17620617 | MGI |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
15805114 | MGI |
| is active in postsynaptic density membrane |
IDA
IDA: Inferred from direct assay
|
26448475 | MGI |
| is active in postsynaptic density membrane |
IEP
IEP: Inferred from expression pattern
|
26448475 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
glutamate receptor ionotropic, kainate 3 |
|