Gtf2i - general transcription factor II I Gene

Also Known as Spin; Diws1t; TFII-I; WBSCR6; BAP-135; GtfII-I; 6030441I21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14886

Summary

Enables mitogen-activated protein kinase binding activity. Acts upstream of or within transition between slow and fast fiber. Located in cell projection; neuronal cell body; and nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; respiratory system; and tooth. Used to study Williams-Beuren syndrome. Orthologous to human GTF2I (general transcription factor IIi). [provided by Alliance of Genome Resources, Apr 2022]

Gtf2i Products (11)

mRNA Protein Name
NM_001080746.2 NP_001074215.1 general transcription factor II-I isoform 1
NM_001080747.2 NP_001074216.1 general transcription factor II-I isoform 3
NM_001080748.2 NP_001074217.1 general transcription factor II-I isoform 4
NM_001080749.2 NP_001074218.1 general transcription factor II-I isoform 5
NM_001359062.1 NP_001345991.1 general transcription factor II-I isoform 1
NM_001359063.1 NP_001345992.1 general transcription factor II-I isoform 2
NM_001359064.1 NP_001345993.1 general transcription factor II-I isoform 2
NM_001359065.1 NP_001345994.1 general transcription factor II-I isoform 3
NM_001359066.1 NP_001345995.1 general transcription factor II-I isoform 4
NM_001359067.1 NP_001345996.1 general transcription factor II-I isoform 4
NM_010365.4 NP_034495.2 general transcription factor II-I isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22899722 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within embryo development IMP
IMP: Inferred from mutant phenotype
19109438 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
22899722 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

general transcription factor II-I

  • BTK-associated protein 135

  • Bruton tyrosine kinase-associated protein 135

  • SRF-Phox1-interacting protein

  • Williams-Beuren syndrome chromosomal region 6 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05903 GTF2I Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20950 Gtf2i Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27467 Gtf2i Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gtf2i NCBI NCBI:2969