Guca1a - guanylate cyclase activator 1a (retina) Gene

Also Known as GC-A; Gcap1; Guca1; mGCAP1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14913

Summary

This gene encodes a calcium-binding photoreceptor protein. The encoded protein may be involved in modulation of guanylyl cyclase activity, and in turn, the mammalian cone phototransduction cascade. Disruption of this gene results in the retinal degeneration associated with cone dystrophy. [provided by RefSeq, Dec 2015]

Guca1a Products (1)

mRNA Protein Name
NM_008189.3 NP_032215.2 guanylyl cyclase-activating protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium sensitive guanylate cyclase activator activity IDA
IDA: Inferred from direct assay
11493703 MGI
enables guanylate cyclase regulator activity IGI
IGI: Inferred from genetic interaction
15336959 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within phototransduction IMP
IMP: Inferred from mutant phenotype
11493703 MGI
acts upstream of or within regulation of guanylate cyclase activity IGI
IGI: Inferred from genetic interaction
15336959 MGI
acts upstream of or within visual perception IMP
IMP: Inferred from mutant phenotype
11493703 MGI
Cellular Component GO Annotation Evidence References Source
located in cone photoreceptor outer segment IDA
IDA: Inferred from direct assay
9620085 MGI
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
9620085 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
22183407 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanylyl cyclase-activating protein 1

  • GCAP 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05915 GUCA1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19509 Guca1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26003 Guca1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Guca1a NCBI NCBI:2978