Hgd - homogentisate 1, 2-dioxygenase Gene

Also Known as Hgo; aku

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15233

Summary

Predicted to enable homogentisate 1,2-dioxygenase activity and identical protein binding activity. Acts upstream of or within cellular amino acid metabolic process. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver; and sensory organ. Used to study alkaptonuria. Human ortholog(s) of this gene implicated in alkaptonuria. Orthologous to human HGD (homogentisate 1,2-dioxygenase). [provided by Alliance of Genome Resources, Apr 2022]

Hgd Products (1)

mRNA Protein Name
NM_013547.3 NP_038575.2 homogentisate 1,2-dioxygenase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables homogentisate 1,2-dioxygenase activity IDA
IDA: Inferred from direct assay
7705358 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within amino acid metabolic process IMP
IMP: Inferred from mutant phenotype
8188247 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homogentisate 1,2-dioxygenase

  • alkaptonuria

  • homogentisate oxygenase

  • homogentisic acid oxidase

  • homogentisicase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103641AS1 (2R)-Octyl-α-hydroxyglutarate-d17 / Unkown
HY-RS06151 HGD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17679 Hgd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24140 Hgd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hgd NCBI NCBI:3081