PRAG1 - PEAK1 related, kinase-activating pseudokinase 1 Gene

Homo sapiens

Also known as NACK; PEAK2; SGK223; PRAGMIN

Gene ID: 157285 | Gene type: protein coding

About PRAG1

Cytogenetic location: 8p23.1 Genomic coordinates (GRCh38): 8:8,317,736-8,386,439 (from NCBI)

This gene has 2 transcripts (splice variants), 207 orthologues and 3 paralogues. Broad expression in thyroid (RPKM 9.5), fat (RPKM 5.5) and 22 other tissues.

Summary

This gene encodes an Enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014]

PRAG1 Products(2)

mRNA	Protein	Name
NM_001080826.3	NP_001074295.2	inactive tyrosine-protein kinase PRAG1
NM_001369759.1	NP_001356688.1	inactive tyrosine-protein kinase PRAG1

Protein Preferred Names

Protein Names

inactive tyrosine-protein kinase PRAG1

PEAK family member 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11047	PRAG1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PRAG1	RGD	RGD:1311793
Bos taurus	PRAG1	VGNC	VGNC:109385
Felis catus	PRAG1	VGNC	VGNC:109511
Macaca mulatta	PRAG1	VGNC	VGNC:109502
Mus musculus	PRAG1	MGD	MGI:1196223
Canis familiaris	PRAG1	VGNC	VGNC:59050

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