ADAD2 - adenosine deaminase domain containing 2 Gene

Homo sapiens

Also known as TENRL

Gene ID: 161931 | Gene type: protein coding

About ADAD2

Cytogenetic location: 16q24.1 Genomic coordinates (GRCh38): 16:84,191,157-84,197,166 (from NCBI)

This gene has 9 transcripts (splice variants), 176 orthologues and 14 paralogues. Restricted expression toward testis (RPKM 19.3).

Summary

Predicted to enable double-stranded RNA Adenosine Deaminase activity; double-stranded RNA binding activity; and tRNA-specific Adenosine Deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to be active in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

ADAD2 Products(2)

mRNA	Protein	Name
NM_001145400.2	NP_001138872.1	adenosine deaminase domain-containing protein 2 isoform 2
NM_139174.4	NP_631913.3	adenosine deaminase domain-containing protein 2 isoform 1

ADAD2 Protein Structure

dsrm

A_deamin

0
100
200
300
400
500
583 a.a.

Protein Preferred Names

Protein Names

adenosine deaminase domain-containing protein 2

Related Diseases

Diseases

Alias

Spinal Canal Intradural Extramedullary Neoplasm

Intradural Extramedullary Spinal Tumors

Intradural Extramedullary Spinal Canal Neoplasm

Tarsal Tunnel Syndrome

Neuropathy Of The Posterior Tibial Nerve And Its Branches	Posterior Tibial Nerve Neuralgia
Compression Of Posterior Tibial Nerve In Tarsal Tunnel

Tibial Neuropathy

Posterior Tibial Neuropathy

Superior Mesenteric Artery Syndrome

Wilkie Syndrome	Wilkie'S Syndrome
Arteriomesenteric Duodenal Compression Syndrome	Cast Syndrome
Vascular Compression Of The Duodenum	Smas
Arteriomesenteric Compression Of Duodenojejunal Flexure

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00263	ADAD2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ADAD2	VGNC	VGNC:37571
Bos taurus	ADAD2	VGNC	VGNC:25602
Rattus norvegicus	ADAD2	RGD	RGD:1586236
Felis catus	ADAD2	VGNC	VGNC:59571
Mus musculus	ADAD2	MGD	MGI:1923023
Macaca mulatta	ADAD2	VGNC	VGNC:69554

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