ADAD2 - adenosine deaminase domain containing 2 Gene

Also Known as TENRL

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 161931

About ADAD2

Cytogenetic location: 16q24.1 Genomic coordinates (GRCh38): 16:84,191,157-84,197,166 (from NCBI)

This gene has 9 transcripts (splice variants), 176 orthologues and 14 paralogues. Restricted expression toward testis (RPKM 19.3).

Summary

Predicted to enable double-stranded RNA Adenosine Deaminase activity; double-stranded RNA binding activity; and tRNA-specific Adenosine Deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to be active in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

ADAD2 Products (2)

mRNA Protein Name
NM_001145400.2 NP_001138872.1 adenosine deaminase domain-containing protein 2 isoform 2
NM_139174.4 NP_631913.3 adenosine deaminase domain-containing protein 2 isoform 1

ADAD2 Protein Structure

dsrm

dsrm: Double-stranded RNA binding motif (117 - 178)

A_deamin

A_deamin: Adenosine-deaminase (editase) domain (261 - 576)

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  • 500
  • 583 a.a.
Protein Preferred Names Protein Names

adenosine deaminase domain-containing protein 2

Related Diseases

Diseases Alias
Spinal Canal Intradural Extramedullary Neoplasm

  • Intradural Extramedullary Spinal Tumors

  • Intradural Extramedullary Spinal Canal Neoplasm
Tarsal Tunnel Syndrome

  • Neuropathy Of The Posterior Tibial Nerve And Its Branches

  • Posterior Tibial Nerve Neuralgia

  • Compression Of Posterior Tibial Nerve In Tarsal Tunnel
Tibial Neuropathy

  • Posterior Tibial Neuropathy
Superior Mesenteric Artery Syndrome

  • Wilkie Syndrome

  • Wilkie'S Syndrome

  • Arteriomesenteric Duodenal Compression Syndrome

  • Cast Syndrome

  • Vascular Compression Of The Duodenum

  • Smas

  • Arteriomesenteric Compression Of Duodenojejunal Flexure
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00263 ADAD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ADAD2 VGNC VGNC:37571
Bos taurus ADAD2 VGNC VGNC:25602
Rattus norvegicus ADAD2 RGD RGD:1586236
Felis catus ADAD2 VGNC VGNC:59571
Mus musculus ADAD2 MGD MGI:1923023
Macaca mulatta ADAD2 VGNC VGNC:69554
Others ADAD2 NCBI