Lamb3 - laminin, beta 3 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16780

Summary

Predicted to be an extracellular matrix structural constituent. Acts upstream of or within brown fat cell differentiation. Located in basement membrane. Part of laminin-5 complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and respiratory system. Used to study junctional epidermolysis bullosa Herlitz type and junctional epidermolysis bullosa non-Herlitz type. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1A; junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Orthologous to human LAMB3 (laminin subunit beta 3). [provided by Alliance of Genome Resources, Apr 2022]

Lamb3 Products (2)

mRNA Protein Name
NM_001277928.1 NP_001264857.1 laminin subunit beta-3 precursor
NM_008484.2 NP_032510.2 laminin subunit beta-3 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within brown fat cell differentiation IDA
IDA: Inferred from direct assay
18492766 MGI
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
8012114 MGI
part of laminin-5 complex IDA
IDA: Inferred from direct assay
9264260 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

laminin subunit beta-3

  • epiligrin subunit bata

  • kalinin B1 chain

  • kalinin subunit beta

  • laminin-5 subunit beta

  • nicein subunit beta

  • nicein, 125kD

  • nicein, 125kDa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07504 LAMB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20978 Lamb3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27495 Lamb3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lamb3 NCBI NCBI:3914