Psmb9 - proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) Gene

Also Known as Lmp2; Lmp-2; Ring12

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16912

Summary

Predicted to enable Proteasome binding activity. Acts upstream of or within antigen processing and presentation and response to bacterium. Part of Proteasome core complex and spermatoproteasome complex. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); lymphoma; and renal cell carcinoma. Orthologous to human PSMB9 (Proteasome 20S subunit beta 9). [provided by Alliance of Genome Resources, Apr 2022]

Psmb9 Products (9)

mRNA Protein Name
NM_001413204.1 NP_001400133.1 proteasome subunit beta type-9 isoform 2
NM_001413205.1 NP_001400134.1 proteasome subunit beta type-9 isoform 3
NM_001413206.1 NP_001400135.1 proteasome subunit beta type-9 isoform 3
NM_001413207.1 NP_001400136.1 proteasome subunit beta type-9 isoform 4
NM_001413208.1 NP_001400137.1 proteasome subunit beta type-9 isoform 5
NM_001413209.1 NP_001400138.1 proteasome subunit beta type-9 isoform 5
NM_001413211.1 NP_001400140.1 proteasome subunit beta type-9 isoform 5
NM_001413212.1 NP_001400141.1 proteasome subunit beta type-9 isoform 6
NM_013585.3 NP_038613.1 proteasome subunit beta type-9 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within antigen processing and presentation IDA
IDA: Inferred from direct assay
15356141 MGI
acts upstream of or within antigen processing and presentation IMP
IMP: Inferred from mutant phenotype
15356141 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
Cellular Component GO Annotation Evidence References Source
part of proteasome core complex IDA
IDA: Inferred from direct assay
16857966 MGI
part of spermatoproteasome complex IDA
IDA: Inferred from direct assay
23706739 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proteasome subunit beta type-9

  • LMP-2d

  • large multifunctional protease 2

  • low molecular mass protein 2

  • macropain chain 7

  • multicatalytic endopeptidase complex chain 7

  • proteasome chain 7

  • proteasome subunit beta-1i

  • proteosome (prosome, macropain) subunit, beta type 9 (large multifunct

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11309 PSMB9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17772 Psmb9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24239 Psmb9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psmb9 NCBI NCBI:5698