Gcsh - glycine cleavage system protein H Gene

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 171133

Summary

Enables aminomethyltransferase activity and enzyme binding activity. Involved in glycine decarboxylation via glycine cleavage system. Located in mitochondrion. Human ortholog(s) of this gene implicated in glycine encephalopathy. Orthologous to human GCSH (glycine cleavage system protein H). [provided by Alliance of Genome Resources, Apr 2022]

Gcsh Products (1)

mRNA Protein Name
NM_133598.2 NP_598282.2 glycine cleavage system H protein, mitochondrial precursor
Molecular Function GO Annotation Evidence 参考文献 由来
enables aminomethyltransferase activity IMP
IMP: Inferred from mutant phenotype
6402507 RGD
enables enzyme binding IPI
IPI: Inferred from physical interaction
6778858 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in glycine decarboxylation via glycine cleavage system IMP
IMP: Inferred from mutant phenotype
6402507 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycine cleavage system H protein, mitochondrial

  • glycine cleavage system protein H (aminomethyl carrier)

  • lipoic acid-containing protein

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Gcsh NCBI NCBI:2653