Mgst1 - microsomal glutathione S-transferase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171341

Summary

Enables glutathione binding activity; glutathione transferase activity; and identical protein binding activity. Involved in several processes, including Leydig cell differentiation; response to lipopolysaccharide; and response to xenobiotic stimulus. Located in several cellular components, including endoplasmic reticulum; mitochondrion; and peroxisomal membrane. Is integral component of membrane. Orthologous to human MGST1 (microsomal Glutathione S-transferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mgst1 Products (1)

mRNA Protein Name
NM_134349.3 NP_599176.1 microsomal glutathione S-transferase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables glutathione binding IDA
IDA: Inferred from direct assay
16806268 RGD
enables glutathione transferase activity IDA
IDA: Inferred from direct assay
7173206 RGD
enables identical protein binding IDA
IDA: Inferred from direct assay
14726533 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
18634816 RGD
Biological Process GO Annotation Evidence References Source
involved in Leydig cell differentiation IEP
IEP: Inferred from expression pattern
15149725 RGD
involved in response to lipopolysaccharide IDA
IDA: Inferred from direct assay
18634816 RGD
involved in response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
17571305 RGD
Cellular Component GO Annotation Evidence References Source
located in apical part of cell IDA
IDA: Inferred from direct assay
9010624 RGD
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
14561759 RGD
is active in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
27913278 RGD
located in membrane IDA
IDA: Inferred from direct assay
16806268 RGD
located in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
2369411 RGD
is active in mitochondrion IDA
IDA: Inferred from direct assay
27913278 RGD
located in peroxisomal membrane IDA
IDA: Inferred from direct assay
16385473 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

microsomal glutathione S-transferase 1

  • microsomal GST-1

  • microsomal GST-I

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08416 MGST1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19219 Mgst1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25708 Mgst1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mgst1 NCBI NCBI:4257