Vsx2 - visual system homeobox 2 Gene

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including negative regulation of cell population proliferation; positive regulation of transcription by RNA polymerase II; and retinal bipolar neuron differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in blindness and isolated microphthalmia 2. Orthologous to human VSX2 (visual system homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]