Crlf2 - cytokine receptor-like factor 2 Gene

Also Known as Crl2; Tpte2; Tslpr

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171499

Summary

Enables cytokine activity. Predicted to be involved in several processes, including positive regulation of interleukin-5 production; positive regulation of mast cell activation; and positive regulation of receptor signaling pathway via STAT. Predicted to act upstream of or within inflammatory response. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Orthologous to human CRLF2 (cytokine receptor like factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Crlf2 Products (1)

mRNA Protein Name
NM_134465.2 NP_604460.2 cytokine receptor-like factor 2 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables cytokine activity IDA
IDA: Inferred from direct assay
11891057 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytokine receptor-like factor 2

  • TSLP receptor

  • thymic stromal lymphopoietin protein receptor

  • thymic stromal-derived lymphopoietin, receptor

  • transmembrane phosphoinositide 3-phosphatase and tensin homolog 2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990767 Solrikitug Inhibitor 99.28% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-151902 SJ988497 Degrader 99.03% Unkown
HY-RS03187 CRLF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18809 Crlf2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25299 Crlf2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991720 Tepilukimig Inhibitor 95.57% Unkown
HY-P991467 RG-7258 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crlf2 NCBI NCBI:64109