Gzmb - granzyme B Gene

Also Known as RNKP-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171528

Summary

Enables serine-type endopeptidase activity. Involved in positive regulation of necroptotic process. Located in early endosome. Orthologous to human GZMB (granzyme B). [provided by Alliance of Genome Resources, Apr 2022]

Gzmb Products (1)

mRNA Protein Name
NM_138517.4 NP_612526.2 granzyme B precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18938146 RGD
enables serine-type endopeptidase activity IDA
IDA: Inferred from direct assay
15123647 RGD
enables serine-type peptidase activity IDA
IDA: Inferred from direct assay
9765264 RGD
Biological Process GO Annotation Evidence References Source
involved in neuron apoptotic process IDA
IDA: Inferred from direct assay
19895873 RGD
involved in positive regulation of necroptotic process IMP
IMP: Inferred from mutant phenotype
19895873 RGD
Cellular Component GO Annotation Evidence References Source
located in early endosome IDA
IDA: Inferred from direct assay
20038786 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

granzyme B

  • GLP I

  • GLP III

  • GLP-1

  • fragmentin

  • granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

  • granzyme-like protein 1

  • granzyme-like protein I

  • natural killer cell protease 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-161982 JNU-0921 Agonist 99.77% Unkown
HY-RS05940 GZMB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17266 Gzmb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-149916 A2AR-antagonist-1 Antagonist 96.68% Unkown
HY-RS23720 Gzmb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gzmb NCBI NCBI:3002