Mcm7 - minichromosome maintenance complex component 7 Gene

Also Known as Mcmd7; mCDC47

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17220

Summary

Enables single-stranded DNA binding activity. Contributes to DNA helicase activity. Acts upstream of or within DNA unwinding involved in DNA replication; cell population proliferation; and cellular response to xenobiotic stimulus. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human MCM7 (minichromosome maintenance complex component 7). [provided by Alliance of Genome Resources, Apr 2022]

Mcm7 Products (3)

mRNA Protein Name
NM_001356576.1 NP_001343505.1 DNA replication licensing factor MCM7 isoform b
NM_001356577.1 NP_001343506.1 DNA replication licensing factor MCM7 isoform b
NM_008568.3 NP_032594.1 DNA replication licensing factor MCM7 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to DNA helicase activity IDA
IDA: Inferred from direct assay
15917436 MGI
contributes to DNA helicase activity IMP
IMP: Inferred from mutant phenotype
12207017 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15917436 MGI
contributes to single-stranded DNA binding IMP
IMP: Inferred from mutant phenotype
12207017 MGI
enables single-stranded DNA binding IPI
IPI: Inferred from physical interaction
15917436 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within DNA unwinding involved in DNA replication IPI
IPI: Inferred from physical interaction
15917436 MGI
acts upstream of or within cell population proliferation IDA
IDA: Inferred from direct assay
12972605 MGI
acts upstream of or within cellular response to xenobiotic stimulus IDA
IDA: Inferred from direct assay
24726645 MGI
Cellular Component GO Annotation Evidence References Source
part of MCM complex IDA
IDA: Inferred from direct assay
10567526 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12972605 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA replication licensing factor MCM7

  • CDC47 homolog

  • mini chromosome maintenance deficient 7

  • minichromosome maintenance deficient 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-180157 CDK2-IN-51 Inhibitor / Unkown
HY-RS08240 MCM7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21373 Mcm7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27892 Mcm7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mcm7 NCBI NCBI:4176