mt-Co1 - cytochrome c oxidase I, mitochondrial Gene

Also Known as CoxI; COX1

Species: Mus musculus (strain: C57BL/6J)

Gene Type: protein coding
Gene ID: 17708

Summary

Enables cytochrome-c oxidase activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, cytochrome c to oxygen; and response to oxidative stress. Located in mitochondrial inner membrane. Part of mitochondrial respiratory chain complex IV. Is expressed in several structures, including brown fat; heart; liver; metanephros; and skeletal muscle. Orthologous to human MT-CO1 (mitochondrially encoded cytochrome c oxidase I). [provided by Alliance of Genome Resources, Apr 2022]

mt-Co1 Products (1)

mRNA Protein Name
NP_904330.1 cytochrome c oxidase subunit I (mitochondrion) [Mus musculus]

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cytochrome-c oxidase activity IDA
IDA: Inferred from direct assay
18729827 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
16815968 MGI
is active in mitochondrion IDA
IDA: Inferred from direct assay
26644517 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
11940593 MGI
part of respiratory chain complex IV IDA
IDA: Inferred from direct assay
24154540 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

  • cytochrome c oxidase subunit I

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16308 mt-Co1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08757 MT-CO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-131453 Mitochondrial respiration-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens mt-Co1 NCBI NCBI:4512