Mybpc3 - myosin binding protein C, cardiac Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17868

Summary

Enables Myosin heavy chain binding activity. Acts upstream of or within several processes, including actin Cytoskeleton organization; cardiac muscle contraction; and regulation of heart rate. Located in A band. Is expressed in several structures, including alimentary system; cardiovascular system; face; liver; and skeleton. Used to study hypertrophic cardiomyopathy 4. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 4. Orthologous to human MYBPC3 (Myosin binding protein C3). [provided by Alliance of Genome Resources, Apr 2022]

Mybpc3 Products (1)

mRNA Protein Name
NM_008653.2 NP_032679.2 myosin-binding protein C, cardiac-type

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables myosin heavy chain binding IPI
IPI: Inferred from physical interaction
17075052 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17075052 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cardiac muscle contraction IMP
IMP: Inferred from mutant phenotype
16224063 MGI
acts upstream of or within heart morphogenesis IMP
IMP: Inferred from mutant phenotype
10532952 MGI
acts upstream of or within myosin filament assembly IMP
IMP: Inferred from mutant phenotype
17254601 MGI
acts upstream of or within regulation of heart contraction IMP
IMP: Inferred from mutant phenotype
14500336 MGI
acts upstream of or within regulation of heart rate IMP
IMP: Inferred from mutant phenotype
10532952 MGI
acts upstream of or within sarcomere organization IMP
IMP: Inferred from mutant phenotype
16224063 MGI
Cellular Component GO Annotation Evidence References Source
located in A band IDA
IDA: Inferred from direct assay
10532952 MGI
located in myofibril IDA
IDA: Inferred from direct assay
10545522 MGI
located in sarcomere IDA
IDA: Inferred from direct assay
17075052 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myosin-binding protein C, cardiac-type

  • cardiac C-protein

  • cardiac MyBP-C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08875 MYBPC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19792 Mybpc3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26288 Mybpc3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mybpc3 NCBI NCBI:4607