Neb - nebulin Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17996

Summary

Predicted to enable actin filament binding activity. Predicted to be involved in cardiac muscle thin filament assembly. Predicted to act upstream of or within regulation of actin filament length and sarcomere organization. Located in Z disc. Is expressed in trunk dermomyotome. Used to study nemaline myopathy 2. Human ortholog(s) of this gene implicated in nemaline myopathy 2. Orthologous to human NEB (nebulin). [provided by Alliance of Genome Resources, Apr 2022]

Neb Products (1)

mRNA Protein Name
NM_010889.1 NP_035019.1 nebulin

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24960163 MGI
Cellular Component GO Annotation Evidence References Source
located in Z disc IDA
IDA: Inferred from direct assay
20368620 MGI
located in contractile muscle fiber IDA
IDA: Inferred from direct assay
20368620 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nebulin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-D0060 4-Di-2-ASP 99.62% Unkown
HY-175107 3-Fluoro-α-ethylaminobutiophenone hydrochloride / Unkown
HY-RS09168 NEB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19566 Neb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26062 Neb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Neb NCBI NCBI:4703