Nme2 - NME/NM23 nucleoside diphosphate kinase 2 Gene

Also Known as NM23B; NM23-H2; nm23-M2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18103

Summary

Predicted to enable several functions, including G-quadruplex DNA binding activity; anion binding activity; and kinase activity. Predicted to be involved in several processes, including negative regulation of myeloid leukocyte differentiation; nucleotide metabolic process; and protein autophosphorylation. Predicted to act upstream of or within nucleotide metabolic process and phosphorylation. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in teratoma. Orthologous to several human genes including NME1-NME2 (NME1-NME2 readthrough). [provided by Alliance of Genome Resources, Apr 2022]

Nme2 Products (2)

mRNA Protein Name
NM_001077529.2 NP_001070997.1 nucleoside diphosphate kinase B
NM_008705.5 NP_032731.1 nucleoside diphosphate kinase B

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nucleoside diphosphate kinase B

  • NDK B

  • NDP kinase B

  • P18

  • expressed in non-metastatic cells 2 protein

  • histidine protein kinase NDKB

  • non-metastatic cells 2, protein (NM23B) expressed in

  • nucleoside-diphosphate kinase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N6747 Stauprimide Inhibitor 99.45% Unkown
HY-W591768 (E)-4-(4-(Dimethylamino)styryl)-1-methylpyridin-1-ium iodide 99.66% Unkown
HY-RS09373 NME2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-170436 NFh-NMe-2 Inducer / Unkown
HY-RS09372 NME1-NME2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19360 Nme2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25852 Nme2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nme2 NCBI NCBI:4831