Odc1 - ornithine decarboxylase, structural 1 Gene

Also Known as ODC

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18263

Summary

Enables ornithine decarboxylase activity and protein homodimerization activity. Involved in putrescine biosynthetic process from ornithine and regulation of protein catabolic process. Acts upstream of or within kidney development and positive regulation of cell population proliferation. Located in cytosol. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study atrichia with papular lesions. Orthologous to human ODC1 (ornithine decarboxylase 1). [provided by Alliance of Genome Resources, Apr 2022]

Odc1 Products (22)

mRNA Protein Name
NM_001409623.1 NP_001396552.1 ornithine decarboxylase isoform 1
NM_001409624.1 NP_001396553.1 ornithine decarboxylase isoform 1
NM_001409627.1 NP_001396556.1 ornithine decarboxylase isoform 1
NM_001409628.1 NP_001396557.1 ornithine decarboxylase isoform 1
NM_001409629.1 NP_001396558.1 ornithine decarboxylase isoform 1
NM_001409630.1 NP_001396559.1 ornithine decarboxylase isoform 1
NM_001409631.1 NP_001396560.1 ornithine decarboxylase isoform 1
NM_001409632.1 NP_001396561.1 ornithine decarboxylase isoform 1
NM_001409633.1 NP_001396562.1 ornithine decarboxylase isoform 1
NM_001409634.1 NP_001396563.1 ornithine decarboxylase isoform 1
NM_001409635.1 NP_001396564.1 ornithine decarboxylase isoform 1
NM_001409636.1 NP_001396565.1 ornithine decarboxylase isoform 1
NM_001409637.1 NP_001396566.1 ornithine decarboxylase isoform 2
NM_001409638.1 NP_001396567.1 ornithine decarboxylase isoform 3
NM_001409639.1 NP_001396568.1 ornithine decarboxylase isoform 4
NM_001409640.1 NP_001396569.1 ornithine decarboxylase isoform 4
NM_001409641.1 NP_001396570.1 ornithine decarboxylase isoform 4
NM_001409642.1 NP_001396571.1 ornithine decarboxylase isoform 4
NM_001409643.1 NP_001396572.1 ornithine decarboxylase isoform 4
NM_001409644.1 NP_001396573.1 ornithine decarboxylase isoform 4
NM_001409645.1 NP_001396574.1 ornithine decarboxylase isoform 4
NM_013614.3 NP_038642.2 ornithine decarboxylase isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ornithine decarboxylase activity IDA
IDA: Inferred from direct assay
8328969 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
24967154 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
16138831 MGI
acts upstream of or within kidney development IMP
IMP: Inferred from mutant phenotype
16138831 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
16138831 MGI
involved in putrescine biosynthetic process from ornithine IDA
IDA: Inferred from direct assay
24967154 MGI
involved in regulation of protein catabolic process IDA
IDA: Inferred from direct assay
24967154 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19449338 MGI
located in cytosol IDA
IDA: Inferred from direct assay
16916800 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ornithine decarboxylase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09750 ODC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13102 SLC25A21 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17072 Odc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23516 Odc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Odc1 NCBI NCBI:4953