Pcsk6 - proprotein convertase subtilisin/kexin type 6 Gene

Also Known as SPC4; Pace4; b2b2830Clo

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18553

Summary

Predicted to enable heparin binding activity; nerve growth factor binding activity; and serine-type endopeptidase activity. Acts upstream of or within determination of left/right symmetry; protein processing; and zygotic determination of anterior/posterior axis, embryo. Predicted to be active in several cellular components, including cell surface; collagen-containing extracellular matrix; and extracellular space. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; limb; and skeleton. Orthologous to human PCSK6 (proprotein convertase subtilisin/kexin type 6). [provided by Alliance of Genome Resources, Apr 2022]

Pcsk6 Products (2)

mRNA Protein Name
NM_001291184.1 NP_001278113.1 proprotein convertase subtilisin/kexin type 6 isoform 2 precursor
NM_011048.1 NP_035178.1 proprotein convertase subtilisin/kexin type 6 isoform 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within determination of left/right symmetry IGI
IGI: Inferred from genetic interaction
10809672 MGI
acts upstream of or within protein processing IMP
IMP: Inferred from mutant phenotype
23918928 MGI
acts upstream of or within zygotic determination of anterior/posterior axis, embryo IGI
IGI: Inferred from genetic interaction
10809672 MGI
acts upstream of or within zygotic determination of anterior/posterior axis, embryo IMP
IMP: Inferred from mutant phenotype
10809672 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proprotein convertase subtilisin/kexin type 6

  • paired basic amino acid cleaving system 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10175 PCSK6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22711 Pcsk6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcsk6 NCBI NCBI:5046