Pemt - phosphatidylethanolamine N-methyltransferase Gene

Also Known as PLMT; PEAMT; PEMT2; Pempt; Pempt2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18618

Summary

Enables S-adenosylmethionine-dependent methyltransferase activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within blastocyst hatching and sphingomyelin biosynthetic process. Located in endoplasmic reticulum membrane. Is expressed in several structures, including central nervous system; early conceptus; liver; lung; and secondary oocyte. Orthologous to human PEMT (phosphatidylethanolamine N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Pemt Products (5)

mRNA Protein Name
NM_001290011.1 NP_001276940.1 phosphatidylethanolamine N-methyltransferase isoform a
NM_001290012.1 NP_001276941.1 phosphatidylethanolamine N-methyltransferase isoform b
NM_001290013.1 NP_001276942.1 phosphatidylethanolamine N-methyltransferase isoform b
NM_001290014.1 NP_001276943.1 phosphatidylethanolamine N-methyltransferase isoform c
NM_008819.3 NP_032845.2 phosphatidylethanolamine N-methyltransferase isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables S-adenosylmethionine-dependent methyltransferase activity IMP
IMP: Inferred from mutant phenotype
25667419 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within blastocyst hatching IMP
IMP: Inferred from mutant phenotype
27869233 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
26113536 MGI
acts upstream of or within sphingomyelin biosynthetic process IMP
IMP: Inferred from mutant phenotype
25667419 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
12072432 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylethanolamine N-methyltransferase

  • phospholipid methyltransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS08831 MUC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10325 PEMT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18490 Pemt Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24972 Pemt Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pemt NCBI NCBI:10400