Ptprf - protein tyrosine phosphatase, receptor type, F Gene

Also Known as LAR; LARS; RPTP-LAR

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19268

Summary

Enables chondroitin sulfate proteoglycan binding activity. Acts upstream of or within neuron projection regeneration and regulation of axon regeneration. Located in neuron projection and neuronal cell body. Is expressed in several structures, including adrenal gland; alimentary system epithelium; central nervous system; genitourinary system; and nasal cavity epithelium. Human ortholog(s) of this gene implicated in hyperinsulinism. Orthologous to human PTPRF (protein tyrosine Phosphatase receptor type F). [provided by Alliance of Genome Resources, Apr 2022]

Ptprf Products (2)

mRNA Protein Name
NM_011213.2 NP_035343.2 receptor-type tyrosine-protein phosphatase F precursor
NM_011213.2 NP_035343.2 receptor-type tyrosine-protein phosphatase F precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables chondroitin sulfate proteoglycan binding IPI
IPI: Inferred from physical interaction
21976490 MGI
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
23791195 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within neuron projection regeneration IMP
IMP: Inferred from mutant phenotype
11438588 MGI
acts upstream of or within regulation of axon regeneration IMP
IMP: Inferred from mutant phenotype
21976490 MGI
acts upstream of or within regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
21976490 MGI
Cellular Component GO Annotation Evidence Références Source
located in neuron projection IDA
IDA: Inferred from direct assay
11438588 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
21976490 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

receptor-type tyrosine-protein phosphatase F

  • leukocyte antigen-related (LAR) PTP receptor

  • leukocyte common antigen related

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS11438 PTPRF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17614 Ptprf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24074 Ptprf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptprf NCBI NCBI:5792