Robo3 - roundabout guidance receptor 3 Gene

Also Known as Rig1; Rbig1; Rig-1; Robo3a; Robo3b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19649

Summary

Involved in axon midline choice point recognition. Acts upstream of or within axon guidance and neuron migration. Located in axon. Is expressed in several structures, including central nervous system; cranial nerve; future brain; head mesenchyme; and sensory organ. Orthologous to human ROBO3 (roundabout guidance receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Robo3 Products (1)

mRNA Protein Name
NM_001164767.1 NP_001158239.1 roundabout homolog 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15084255 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within axon guidance IDA
IDA: Inferred from direct assay
15084255 MGI
involved in axon guidance IDA
IDA: Inferred from direct assay
30843071 MGI
acts upstream of or within axon guidance IGI
IGI: Inferred from genetic interaction
15084255 MGI
acts upstream of or within axon guidance IMP
IMP: Inferred from mutant phenotype
15084255 MGI
involved in axon guidance IMP
IMP: Inferred from mutant phenotype
25433640 MGI
involved in axon midline choice point recognition IMP
IMP: Inferred from mutant phenotype
18986510 MGI
involved in commissural neuron axon guidance IMP
IMP: Inferred from mutant phenotype
18466743 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
15233918 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
19906978 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

roundabout homolog 3

  • retinoblastoma inhibiting gene 1

  • retinoblastoma-inhibiting gene 1 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12112 ROBO3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21038 Robo3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27555 Robo3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Robo3 NCBI NCBI:64221