1. Gene
  2. Rxrg - retinoid X receptor gamma Gene

Rxrg - retinoid X receptor gamma Gene

Mus musculus

Also known as Nr2b3

Gene ID: 20183 | Gene type: protein coding

About Rxrg

Chromosome 1: 167,425,953-167,467,192 forward strand.GRCm39:CM000994.3

This gene has 4 transcripts (splice variants), 277 orthologues, 11 paralogues and is associated with 9 phenotypes. Biased expression in heart adult (RPKM 24.1), CNS E18 (RPKM 1.1) and 1 other tissues.

Summary

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; identical protein binding activity; and nuclear receptor activity. Acts upstream of or within positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus and retinoic acid receptor signaling pathway. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; musculature; and sensory organ. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human RXRG (retinoid X receptor gamma). [provided by Alliance of Genome Resources, Apr 2022]

Rxrg Products(2)

mRNA Protein Name
NM_001159731.1 NP_001153203.1 retinoic acid receptor RXR-gamma isoform 2
NM_009107.3 NP_033133.1 retinoic acid receptor RXR-gamma isoform 1

Rxrg Protein Structure

Nuc_recep-AF1

Nuc_recep-AF1: pfam11825 (24 - 133)

NR_DBD_RXR

NR_DBD_RXR: cd06956 (136 - 212)

NR_LBD_RXR_like

NR_LBD_RXR_like: cd06943 (232 - 440)

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  • 463 a.a.
Protein Preferred Names Protein Names

retinoic acid receptor RXR-gamma

nuclear receptor subfamily 2 group B member 3

Orthologs Information

Species Symbol Source ID
Homo sapiens Rxrg NCBI NCBI:6258