ADAM32 - ADAM metallopeptidase domain 32 Gene

Homo sapiens

Gene ID: 203102 | Gene type: protein coding

About ADAM32

Cytogenetic location: 8p11.22 Genomic coordinates (GRCh38): 8:39,107,529-39,284,917 (from NCBI)

This gene has 11 transcripts (splice variants), 1 gene allele, 362 orthologues and 20 paralogues. Restricted expression toward testis (RPKM 20.2).

Summary

This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

ADAM32 Products(2)

mRNA	Protein	Name
NM_001313994.1	NP_001300923.1	disintegrin and metalloproteinase domain-containing protein 32 isoform 2
NM_145004.7	NP_659441.4	disintegrin and metalloproteinase domain-containing protein 32 isoform 1 preproprotein

ADAM32 Protein Structure

Pep_M12B_propep

Reprolysin

Disintegrin

ADAM_CR

0
200
400
600
787 a.a.

Protein Preferred Names

Protein Names

disintegrin and metalloproteinase domain-containing protein 32

a disintegrin and metalloprotease domain 32

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00283	ADAM32 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ADAM32	MGD	MGI:2653822
Canis familiaris	ADAM32	VGNC	VGNC:37584
Bos taurus	ADAM32	VGNC	VGNC:25610
Rattus norvegicus	ADAM32	RGD	RGD:735114
Others	ADAM32	NCBI

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