St3gal4 - ST3 beta-galactoside alpha-2,3-sialyltransferase 4 Gene

Also Known as Siat4c; SIAT4-C; ST3GalIV; ST3Gal IV

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20443

Summary

Enables N-acetyllactosaminide alpha-2,3-sialyltransferase activity and beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Involved in positive regulation of blood coagulation and positive regulation of leukocyte tethering or rolling. Acts upstream of or within protein glycosylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; integumental system; and nervous system. Orthologous to human ST3GAL4 (ST3 beta-galactoside alpha-2,3-sialyltransferase 4). [provided by Alliance of Genome Resources, Apr 2022]

St3gal4 Products (1)

mRNA Protein Name
NM_009178.4 NP_033204.2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables N-acetyllactosaminide alpha-2,3-sialyltransferase activity IMP
IMP: Inferred from mutant phenotype
12097641 MGI
enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IDA
IDA: Inferred from direct assay
9184827 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of blood coagulation IMP
IMP: Inferred from mutant phenotype
12097641 MGI
involved in positive regulation of leukocyte tethering or rolling IMP
IMP: Inferred from mutant phenotype
25498912 MGI
acts upstream of or within protein glycosylation IDA
IDA: Inferred from direct assay
9184827 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

  • N-acetyllactosaminide alpha-2,3-sialyltransferase

  • alpha 2,3-ST 4

  • alpha 2,3-sialyltransferase IV

  • beta-galactoside alpha-2,3-sialyltransferase 4

  • gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase

  • gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase

  • gal-beta-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13849 ST3GAL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18209 St3gal4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24686 St3gal4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens St3gal4 NCBI NCBI:6484