1. Gene
  2. Slc10a2 - solute carrier family 10, member 2 Gene

Slc10a2 - solute carrier family 10, member 2 Gene

Mus musculus

Also known as ASBT; IBAT; ISBT; 9130221J18Rik

Gene ID: 20494 | Gene type: protein coding

About Slc10a2

Chromosome 8: 5,133,219-5,155,351 reverse strand.GRCm39:CM001001.3

This gene has 1 transcript (splice variant), 213 orthologues, 6 paralogues and is associated with 13 phenotypes. Biased expression in large intestine adult (RPKM 2.9), kidney adult (RPKM 7.5) and 2 other tissues.

Summary

Predicted to enable bile acid:sodium symporter activity. Acts upstream of or within response to bacterium. Located in apical plasma membrane and microvillus. Is expressed in Peyer's patch; genitourinary system; and small intestine. Human ortholog(s) of this gene implicated in intestinal disease. Orthologous to human SLC10A2 (solute carrier family 10 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc10a2 Products(1)

mRNA Protein Name
NM_011388.3 NP_035518.1 ileal sodium/bile acid cotransporter

Slc10a2 Protein Structure

bass

bass: TIGR00841 (28 - 313)

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  • 348 a.a.
Protein Preferred Names Protein Names

ileal sodium/bile acid cotransporter

Na(+)-dependent ileal bile acid transporter

apical sodium-dependent bile acid transporter

ileal Na(+)/bile acid cotransporter

ileal sodium-dependent bile acid transporter

sodium/taurocholate cotransporting polypeptide, ileal

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc10a2 NCBI NCBI:6555