Slc10a2 - solute carrier family 10, member 2 Gene
Also Known as ASBT; IBAT; ISBT; 9130221J18Rik
Species: Mus musculus
About Slc10a2
This gene has 1 transcript (splice variant), 213 orthologues, 6 paralogues and is associated with 13 phenotypes. Biased expression in large intestine adult (RPKM 2.9), kidney adult (RPKM 7.5) and 2 other tissues.
Summary
Predicted to enable bile acid:sodium symporter activity. Acts upstream of or within response to bacterium. Located in apical plasma membrane and microvillus. Is expressed in Peyer's patch; genitourinary system; and small intestine. Human ortholog(s) of this gene implicated in intestinal disease. Orthologous to human SLC10A2 (solute carrier family 10 member 2). [provided by Alliance of Genome Resources, Apr 2022]
Slc10a2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_011388.3 | NP_035518.1 | ileal sodium/bile acid cotransporter |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within response to bacterium |
IEP
IEP: Inferred from expression pattern
|
23012479 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in apical plasma membrane |
IDA
IDA: Inferred from direct assay
|
23747249 | MGI |
| located in microvillus |
IDA
IDA: Inferred from direct assay
|
23200860 | MGI |
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Slc10a2 Protein Structure
bass: TIGR00841 (28 - 313)
- 0
- 100
- 200
- 300
- 348 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ileal sodium/bile acid cotransporter |
|
|