Esrp1 - epithelial splicing regulatory protein 1 Gene

Predicted to enable mRNA binding activity. Involved in regulation of RNA splicing and regulation of inner ear auditory receptor cell fate specification. Acts upstream of or within alternative mRNA splicing, via spliceosome; morphogenesis of a branching epithelium; and positive regulation of epithelial cell proliferation. Predicted to be located in nuclear body. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; branchial arch; extraembryonic component; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 109. Orthologous to human ESRP1 (epithelial splicing regulatory protein 1). [provided by Alliance of Genome Resources, Apr 2022]