Adgrb3 - adhesion G protein-coupled receptor B3 Gene

Also Known as Bai3; A830096D10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 210933

Summary

Enables GTPase activator activity. Involved in regulation of dendrite morphogenesis. Acts upstream of or within several processes, including motor learning; neuron remodeling; and positive regulation of synapse assembly. Located in postsynapse and synaptic cleft. Is expressed in several structures, including brain; lung; skeletal muscle; and testis. Orthologous to human ADGRB3 (adhesion G protein-coupled receptor B3). [provided by Alliance of Genome Resources, Apr 2022]

Adgrb3 Products (1)

mRNA Protein Name
NM_175642.4 NP_783573.4 adhesion G protein-coupled receptor B3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
23628982 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21262840 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within maintenance of synapse structure IMP
IMP: Inferred from mutant phenotype
25611509 MGI
acts upstream of or within motor learning IGI
IGI: Inferred from genetic interaction
25611509 MGI
acts upstream of or within neuron remodeling IGI
IGI: Inferred from genetic interaction
25611509 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
involved in regulation of dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
23628982 MGI
involved in regulation of synapse maturation IDA
IDA: Inferred from direct assay
25611509 MGI
involved in regulation of synapse maturation IMP
IMP: Inferred from mutant phenotype
25611509 MGI
involved in regulation of synapse pruning IDA
IDA: Inferred from direct assay
25611509 MGI
involved in regulation of synapse pruning IMP
IMP: Inferred from mutant phenotype
25611509 MGI
Cellular Component GO Annotation Evidence References Source
is active in cerebellar climbing fiber to Purkinje cell synapse IDA
IDA: Inferred from direct assay
25611509 MGI
is active in cerebellar climbing fiber to Purkinje cell synapse IMP
IMP: Inferred from mutant phenotype
25611509 MGI
located in postsynapse IDA
IDA: Inferred from direct assay
25611509 MGI
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
25611509 MGI
located in synaptic cleft IDA
IDA: Inferred from direct assay
25611509 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adhesion G protein-coupled receptor B3

  • G protein-coupled receptor BAI3

  • brain-specific angiogenesis inhibitor 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00347 ADGRB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21813 Adgrb3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28329 Adgrb3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adgrb3 NCBI NCBI:577