Cln5 - ceroid-lipofuscinosis, neuronal 5 Gene

Also Known as A730075N08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 211286

Summary

Predicted to enable hydrolase activity, acting on glycosyl bonds and mannose binding activity. Acts upstream of or within lysosome organization and visual perception. Located in lysosome and vacuolar lumen. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and spleen. Used to study neuronal ceroid lipofuscinosis 5. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 5. Orthologous to human CLN5 (CLN5 intracellular trafficking protein). [provided by Alliance of Genome Resources, Apr 2022]

Cln5 Products (1)

mRNA Protein Name
NM_001033242.1 NP_001028414.1 ceroid-lipofuscinosis neuronal protein 5 homolog precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables long-chain fatty acyl-CoA hydrolase activity IDA
IDA: Inferred from direct assay
35427157 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19941651 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within lysosome organization IMP
IMP: Inferred from mutant phenotype
15459177 MGI
acts upstream of or within visual perception IMP
IMP: Inferred from mutant phenotype
15459177 MGI
Cellular Component GO Annotation Evidence References Source
located in lysosome IDA
IDA: Inferred from direct assay
15207259 MGI
located in vacuolar lumen IDA
IDA: Inferred from direct assay
15207259 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ceroid-lipofuscinosis neuronal protein 5 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02823 CLN5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22122 Cln5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28644 Cln5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cln5 NCBI NCBI:1203